"Game Over"s are the screens that cause you to lose the game.
Scared Your Love
When you drag a body, murder, or are seen with a weapon by a corpse around Makio, he will say, "You Monster!" and cause a game over.
Caught by the Teacher
The teacher will chokehold Akari, attempting to cause her to pass out. This will cause a game over.
This rule applies to justice-minded students as well.